| | Runs | playerId | seasonId | clubId | matchId | Runs | Player | Team | Season | Grade | Round | Inns | Opponent |
| 1 | 99 | 1206489 | 155 | 32736 | 3940209 | 99 | Harpreet Sandhu | Pashtun All Nations | 2021/2022 | SAMCA Metropolitan Twenty20 Champions Cup | 2 | 1 | Morphettville Park |
| 2 | 76 | 1663631 | 155 | 1039 | 3940217 | 76 | Tom E Parton | Para Hills | 2021/2022 | SAMCA Metropolitan Twenty20 Champions Cup | SF | 1 | Adelaide Rockets |
| 3 | 56 | 715597 | 155 | 1550 | 3940201 | 56* | Matthew Scott | Morphettville Park | 2021/2022 | SAMCA Metropolitan Twenty20 Champions Cup | 1 | 1 | Cove |
| 4 | 53 | 427689 | 155 | 8657 | 3940206 | 53* | Timothy J Davey | Adelaide Rockets | 2021/2022 | SAMCA Metropolitan Twenty20 Champions Cup | 1 | 1 | Hope Valley |
| 5 | 51 | 694312 | 155 | 1028 | 3940205 | 51* | Harry W Hockney | Prince Alfred Old Collegians | 2021/2022 | SAMCA Metropolitan Twenty20 Champions Cup | 1 | 1 | Para Hills |
Note: Qualification levels for this report are 50 and 100 runs.
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